Agharkar Research Institute

Center for Nanobioscience (CNB)

 

The essence of nanotechnology is the creation and utilization of materials and devices at the level of atoms and molecules and the exploitation of unique properties and phenomena at the nanoscale. Over the next two decades or so, fields of medicine, surgery, medical diagnostics, treatment, paints, cosmetics, data storage systems etc. will be completely revolutionized by employing materials, components, devices and instruments developed by nanotechnology.

 

Realizing the importance of nanotechnology, concerted efforts were made to develop a strong Nanobioscience programme at Agharkar Research Institute with a focus of research on the application of nanoscience and technology for the improvement of agriculture, human health and environment.

 

CNB has mastered a new approach of ‘Materials Science and Engineering through Microbiology’ to develop eco-friendly methods for the synthesis of metal-based nanomaterials.  Some of the applications of nanomaterials already demonstrated include use of semiconductor nanoparticles in electronic devices such as diodes; development of ‘biostablized silver nanoparticles’ based ointment for the treatment of burns, wounds, and pressure wounds (bed sores); use of iron-palladium bimetallic nanoparticles for rapid and complete degradation of chlorinated pesticides from drinking water; synthesis of manganite systems for safe cancer hyperthermia treatment, etc. Our studies on traditional Indian medicine, viz. Ayurvedic bhasma preparation using concepts of nanoscience not only reveal their submicronic nature but throw light on possible mode of action.

 

Some specific research projects being carried out at present are:

 

  • biostabilized silver nanoparticles based formulations as topical antimicrobial agents
  • super paramagnetic nanoparticles in treatment of cancer by hyperthermia
  • bimetallic nanoparticles for catalytic degradation of pesticides and dyes
  • bacterial surface layer proteins as templates for synthesis and assembly of nanoparticles
  • in-vitro and in-vivo toxicity studies of nanomaterials
  • nanomaterials for the control of diabetes mellitus
  • development of nanotechnology based methods for rapid diagnosis of microbial diseases
  • long-term preservation of biomolecules in nanostructures of natural origin
  • hyper-expression of phytochelatin synthesis genes for the production of semiconductor metal sulfide  nanoparticles  and micronutrient-enriched yeasts
  • nanomaterials for delivery of pesticides and fertilizers

 

CNB has active collaborations with a number of highly reputed institutions and universities in India and abroad. It is in the final stages of initiating post-graduate courses to impart high quality education in nanobioscience and nanotechnology.

 




Research Positions in Nanobioscience
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       ********* “SILVER NANO GEL” AMONG THE TOP SIX FOR “INNOVATION AWARDS” AT CPhI WORLDWIDE 2008, FRANKFURT, GERMANY. THE TECHNOLOGY WAS DEVELOPED BY ARI’S CENTRE FOR NANOBIOSCIENCE AND LICENSED TO KHANDELWAL LABORATORIES, MUMBAI